FIGURE 5 | A hierarchy of evidence.

From the following article:

Development of therapeutics: opportunities within complementary and alternative medicine

Linda W. Engel & Stephen E. Straus

Nature Reviews Drug Discovery 1, 229-237 (March 2002)

doi:10.1038/nrd750

Development of therapeutics: opportunities within complementary and alternative medicine

The National Center for Complementary and Alternative Medicine (NCCAM) relies on evidence-based reviews to help identify areas for clinical investigation. The information regarding the efficacy and safety of complementary and alternative medicine (CAM) therapies spans a continuum that ranges from anecdotes and retrospective studies to small randomized controlled (Phase II) clinical trials, and Phase III trials.

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