Table of contents
October 2002 Vol 1 No 10
In this issue
p741 | doi:10.1038/nrd933
Editorial: Prescription drug user fees: improvement at a price?
p743 | doi:10.1038/nrd927
Research Highlights
Computational chemistry: Panning for gold
p745 | doi:10.1038/nrd922
Therapeutic proteins: High affinity good, lower affinity better
p746 | doi:10.1038/nrd923
Neurodegenerative diseases: Tying up loose ends
p746 | doi:10.1038/nrd931
Structure-based drug design: Reiterating the point
p747 | doi:10.1038/nrd930
Antibacterial drugs: Stitching together naturally
p748 | doi:10.1038/nrd921
Neurodegenerative diseases: Netting the aggregate
p748 | doi:10.1038/nrd928
G-Protein-coupled receptors: Lipidated peptides: a therapeutic tool kit
p749 | doi:10.1038/nrd929
In brief
Biotechnology | Inflammatory diseases | Chemical-library design | Anticancer drugs
p749 | doi:10.1038/nrd935
Ligands: Sorting good from bad
p750 | doi:10.1038/nrd932
News and Analysis
Patent watch
Opposition division goes to Edinburgh | US patent office, interfering again
p750 | doi:10.1038/nrd936
From the analyst's couch
Drug life-cycle technologies
p751 | doi:10.1038/nrd926
Reviews
Putting chirality to work: the strategy of chiral switches
Israel Agranat, Hava Caner & John Caldwell
p753 | doi:10.1038/nrd915
Structural biology of insulin and IGF1 receptors: implications for drug design
Pierre De Meyts & Jonathan Whittaker
p769 | doi:10.1038/nrd917
Discoveries, drugs and skeletal disorders
David Goltzman
p784 | doi:10.1038/nrd916
Toll-like receptors as potential therapeutic targets for multiple diseases
Claudia Zuany-Amorim, John Hastewell & Christoph Walker
p797 | doi:10.1038/nrd914
G-Protein-coupled receptor oligomerization and its potential for drug discovery
Susan R. George, Brian F. O'Dowd & Samuel P. Lee
p808 | doi:10.1038/nrd913
Perspectives
Outlook
Two decades of orphan product development
Marlene E. Haffner, Janet Whitley & Marie Moses
p821 | doi:10.1038/nrd919
Opinion
Can intellectualism stifle scientific discovery?
Richard A. Bond
p825 | doi:10.1038/nrd918
Careers and Recruitment
Employment and employability for pharmacology graduates
Ian Hughes
p833 | doi:10.1038/nrd925
