Figures and Tables
From the following article:
Discoveries, drugs and skeletal disorders
David Goltzman
Nature Reviews Drug Discovery 1, 784-796 (October 2002)
doi:10.1038/nrd916
Figure 1
Osteoblast–osteoclast interactions.
Figure 2
Osteoblast development and presumed sites of regulation by PTH and PTHrP.
Figure 3
Model of regulation of osteoblast function by the LRP5 signalling system.
Figure 4
Osteoclast action.
Figure 5
Structures of selected non-nitrogen-containing and nitrogen-containing bisphosphonates.
Figure 6
Chemical structures of compounds that act through the oestrogen receptor.
Figure 7
Model of endochondral bone formation and selected molecular regulators.
Table 1
Clinically useful drugs (selected) for skeletal disorders
Table 2
Selected drugs in development for systemic or local use in skeletal disorders
