Liver metastases from colorectal cancer: radioembolization with systemic therapy
Nils H. Nicolay, David P. Berry & Ricky A. Sharma
Published online: 03 November 2009 | doi:10.1038/nrclinonc.2009.165
Most patients with advanced colorectal cancer die from hepatic metastases. Radioembolization is a technique for administering radiotherapy internally to unresectable primary or secondary hepatic malignancies in a single procedure to improve local control of disease. This technique enables significant downsizing of liver metastases to permit subsequent resection. The rationale for this approach combined with cytotoxic and molecularly targeted agents is discussed.
