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Nature Reviews Clinical Oncology 6, 624–626 (1 November 2009) | doi:10.1038/nrclinonc.2009.159

Hematology: Follicular lymphoma: maintenance therapy is (often) indicated

John F. Seymour

Disseminated follicular lymphoma remains incurable despite recent advances in therapy (with the exception of allogeneic transplantation). Each episode of disease recurrence and re-treatment is associated with impaired quality of life (QOL); however, the quality of response and duration of remission tend to diminish with each cycle of relapse and re-treatment.