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Research Highlights
Nature Reviews Clinical Oncology 6, 2 (1 January 2009) | doi:10.1038/ncponc1264
Allele-specific expression of TGFBR1 is linked to an increased risk of colorectal cancer
Abstract
Valle L et al. (2008) Germline allele-specific expression of TGFBR1 confers an increased risk of colorectal cancer. Science 321: 1361–1365 Genetic variation influences predisposition to colorectal cancer and, although alleles associated with an increased risk have been identified, much of the genetic basis of this predisposition remains unexplained.
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