TABLE 2  Randomized studies of planned radiation followed by cystectomy versus definitive radiation followed by salvage cystectomy.

From the following article:

Chemotherapy for muscle-invasive bladder cancer treated with definitive radiotherapy: persisting uncertainties

Toni K Choueiri and Derek Raghavan

Nature Clinical Practice Oncology (2008) 5, 444-454
doi:10.1038/ncponc1159

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ReferenceNumber of patientsTumor stageTherapyLong-term survival (3–5 years)

Abbreviations: NS, not significant; RT, radiotherapy.

Miller (1977)2868T2–T3RT (50 Gy) plus cystectomy vs RT (70 Gy) followed by salvage cystectomy46% vs 16% (P <0.01)
Bloom et al. (1982)29189T3RT (40 Gy) plus cystectomy vs RT (60 Gy) followed by salvage cystectomy38% vs 29% (P = NS)
Sell et al. (1991)30183T2–T4aRT (40 Gy) plus cystectomy vs RT (60 Gy) followed by salvage cystectomy20% vs 20% (P = NS)

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