FIGURE 2 Schematic example of an isobologram depicting the combination of radiation and a systemic agent.
From the following article:
The concurrent chemoradiation paradigm—general principles
Tanguy Y Seiwert, Joseph K Salama and Everett E Vokes
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Figure 2. Schematic example of an isobologram depicting the combination of radiation and a systemic agent.
The x and y axes show the isoeffective levels for radiation and drug. The thick line is the line of additivity, and the additivity envelope is based on the combined standard errors. Curves above the envelope represent antagonistic effects and curves below the envelope represent 'synergistic' effects.1, 41 Abbreviation: RT, radiotherapy.
