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Research Highlights
Nature Reviews Clinical Oncology 3, 6 (1 January 2006) | doi:10.1038/ncponc0324
No link between AIB1 variation and increased breast cancer risk in BRCA1/2-mutation carriers
Abstract
Hughes DJ et al. (2005) Breast cancer risk in BRCA1 and BRCA2 mutation carriers and polyglutamine repeat length in the AIB1 gene. Int J Cancer 117: 230–233 Although germline alterations in the breast cancer susceptibility genes BRCA1 and BRCA2 are known to be associated with a high overall lifetime risk of breast and ovarian cancer, there is a great deal of variability in cancer-risk estimates between different analyses.
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