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Nature Reviews Clinical Oncology 2, 333 (1 July 2005) | doi:10.1038/ncponc0217

Mitochondrial mutations and colorectal cancer prognosis

Li|[egrave]|vre A et al. (2005) Clinical value of mitochondrial mutations in colorectal cancer. J Clin Oncol 23: 3517–3525 Human mitochondrial DNA (mtDNA) is thought to be more prone to mutations than nuclear DNA, and mutations within this 16,569 base-pair genome have been reported in different types of cancers.