FIGURE 3  Lymph-node biopsy with hematoxylin and eosin and Ki-67 nuclear proliferation antigen staining.

From the following article:

COX2-related multicentric mixed-type Castleman's disease in a young man

Jie Liu, Shuang Han, Jie Ding, Kaichun Wu, Jiyan Miao and Daiming Fan

Nature Clinical Practice Oncology (2005) 2, 370-375
doi:10.1038/ncponc0219

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Figure 3.  Lymph-node biopsy with hematoxylin and eosin and Ki-67 nuclear proliferation antigen staining.

(A) Hematoxylin and eosin staining showing abnormal blood vessel penetration into the follicles accompanied by hyalinization and multilayer lymphocytes with circular permutation surrounding the follicle to form onion-skin architecture (arrow). Magnification times200. (B) Proliferating cells in the germinal center highlighted by Ki-67 staining (DAKO, Carpinteria, CA). Magnification times200. (C) Proliferating blood vessels highlighted by Ki-67 staining. Magnification times200.

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