TABLE 1  Cumulative analysis of 187 patients with myelodysplastic syndrome treated with low-dose decitabinea

From the following article:

Optimizing therapy with methylation inhibitors in myelodysplastic syndromes: dose, duration, and patient selection

Jean-Pierre Issa

Nature Clinical Practice Oncology (2005) 2, S24-S29
doi:10.1038/ncponc0355

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OutcomeNo.(%)

aSummary of outcomes in several phase II studies of decitabine in elderly patients with high-risk myelodysplastic syndrome.28

Toxic death12 (6)
Progressive disease33 (18)
Stable disease39 (16)
Hematologic improvement26 (14)
Partial response19 (10)
Complete response47 (25)
Not evaluable11 (6)
Total response92 (49)
Median survival15 months
Two-year survival rate34%

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