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Nature Reviews Clinical Oncology 2, 596–597 (1 December 2005) | doi:10.1038/ncponc0360

The evolving role of aromatase inhibitors in the treatment of early-stage breast cancer

Paula D Ryan & Paul E Goss

Substantial progress has been made using aromatase inhibitors in early-stage breast cancer. This article highlights results from recent and ongoing trials of aromatase inhibitors as adjuvant therapy and discusses options for integration of these agents with tamoxifen in various subsets of patients and clinical scenarios.