In 2016, novel findings on the role of predisposing gene variants in sarcoma oncogenesis were published, as well as studies addressing novel molecular classifications and results from randomized controlled trials highlighting successful new treatments. Herein, we discuss these meaningful advances.
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Acknowledgements
J-Y.B. receives support from Association DAM's, Ensemble contre Le GIST, Eurosarc (FP7-278742), Fondation ARC, Infosarcome, InterSARC (INCA), LabEx DEvweCAN (ANR-10-LABX-0061), Ligue de L'Ain contre le Cancer, LYric (DGOS-INCa-4664), NetSARC and RREPS (both INCA). I. R-C. receives support from Association DAM's, Fondation ARC, Ligue de L'Ain contre le Cancer, LYric (DGOS-INCa-4664), NetSARC (INCA) and RREPS (INCA).
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J-Y.B. receives research support and honoraria from Eisai, Eli Lilly, GSK, Ignyta, Novartis, Pharmamar and Roche. I.R-C. receives research support and honoraria from Eli Lilly, Pharmamar and Roche.
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Blay, JY., Ray-Coquard, I. Evolving biological understanding and treatment of sarcomas. Nat Rev Clin Oncol 14, 78–80 (2017). https://doi.org/10.1038/nrclinonc.2016.200
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DOI: https://doi.org/10.1038/nrclinonc.2016.200
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