Newly published data indicate the sensitivity of 18F-fluorodeoxyglucose (18F-FDG)–PET for the detection of recurrent disease. A total of 88 patients with no, or equivocal signs of recurrence on clinical examination, but who had raised carcinoembryonic antigen (CEA) levels were examined using 18F-FDG–PET. Recurrent disease was detected in 56 patients, 49 of whose disease was identified using 18F-FDG–PET, with a sensitivity and specificity of 88%. Many of these patients went on to receive treatment with curative intent, thus indicating the importance of early detection of recurrent disease.
References
Khan, K. et al. Survival outcomes in asymptomatic patients with normal conventional imaging but raised carcinoembryonic antigen levels in colorectal cancer following positron emission tomography-computed tomography imaging. Oncologist. http://dx.doi.org/10.1634/theoncologist.2016-0222 (2016).
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Sidaway, P. Recurrent disease detected using FDG–PET. Nat Rev Clin Oncol 14, 3 (2017). https://doi.org/10.1038/nrclinonc.2016.176
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DOI: https://doi.org/10.1038/nrclinonc.2016.176