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Nature Reviews Clinical Oncology 1, 60 (1 December 2004) | doi:10.1038/ncponc0029

Reduced postoperative chemotherapy for Wilms' tumor

de Kraker J et al. (2004) Reduction of postoperative chemotherapy in children with stage I intermediate-risk and anaplastic Wilms' tumour (SIOP 93-01 trial): a randomised controlled trial. Lancet 364: 1229–1235 High rates of recurrence-free and overall survival have been achieved for Wilms' tumor, so the emphasis of current research is on reducing treatment-related toxicity.