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Nature Reviews Clinical Oncology 1, 60 (1 December 2004) | doi:10.1038/ncponc0028

Surgical practice patterns in stage IV colorectal cancer

Temple LKF et al. (2004) Use of surgery among elderly patients with stage IV colorectal cancer. J Clin Oncol 22: 3475–3484 In asymptomatic patients with stage IV colorectal cancer and unresectable metastases, the net benefit of resection of the primary tumor is unclear.