Review

Nature Reviews Cardiology 6, 689-698 (November 2009) | doi:10.1038/nrcardio.2009.162

Subject Categories: Infection | Prevention

Prevention and treatment of rheumatic heart disease in the developing world

Andrew C. Steer1 & Jonathan R. Carapetis2  About the authors

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The prevalence of rheumatic heart disease (RHD) in industrialized countries has declined dramatically over the last century, but the disease remains an important global health problem with the burden of disease shouldered by developing countries. Indeed, data from epidemiologic surveys, which used echocardiography as the primary screening tool, indicate that the prevalence of RHD in developing nations might have been substantially underestimated. Despite the high burden of disease globally, there has never been a sustained and comprehensive international strategy to control RHD. The current focus of global efforts to combat the disease is on strengthening secondary prophylaxis strategies, although very few active national programs have been implemented. RHD will continue to cause high morbidity and mortality among the world's poorest populations unless current prevention initiatives expand and new programs are established.

Author affiliations

Centre for International Child Health, University of Melbourne, Parkville, Vic, Australia. (A C Steer). Menzies School of Health Research, Charles Darwin University, Darwin, NT, Australia. (J R Carapetis).

Correspondence to: A C Steer Email: andrew.steer@rch.org.au

Published online 15 September 2009

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