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A case of Takotsubo cardiomyopathy mimicking an acute coronary syndrome

Abstract

Background A 71-year-old woman presented with severe chest pain after an episode of acute emotional distress. Her serum levels of cardiac enzymes were slightly elevated and electrocardiography revealed anterior ST-segment elevations. Significant coronary stenoses were excluded. A left ventriculogram revealed apical ballooning and a hypercontractile basal segment.

Investigations Serum cardiac enzyme measurements, echocardiography, coronary angiography and left ventriculography.

Diagnosis Takotsubo cardiomyopathy

Management Treatment with β-blockers, aspirin, angiotensin-converting-enzyme inhibitors, and intravenous diuretics.

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Figure 1: A 12-lead electrocardiogram showing ST-segment elevations and T-wave inversions in the right precordial leads, which is a typical pattern observed in Takotsubo cardiomyopathy.
Figure 2: Left ventriculogram of the patient during systole showing mid, distal and apical left ventricular ballooning, with vigorous contraction of the basal segment as seen in Takotsubo cardiomyopathy.

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Correspondence to Robert J Ostfeld.

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Metzl, M., Altman, E., Spevack, D. et al. A case of Takotsubo cardiomyopathy mimicking an acute coronary syndrome. Nat Rev Cardiol 3, 53–56 (2006). https://doi.org/10.1038/ncpcardio0414

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