The procedural efficacy of a new optical coherence tomography (OCT) strategy to guide percutaneous coronary intervention (PCI) is similar to that with intravascular ultrasonography (IVUS) or angiography, according to a randomized, controlled trial (ILUMIEN III: OPTIMIZE PCI) involving 450 patients. The final median minimum stent area (primary end point) was 5.79 mm2; with OCT guidance, 5.89 mm2; with IVUS guidance, and 5.49 mm2; with angiography guidance. The investigators now plan to test the OCT strategy in a clinical outcome trial.
References
Ali, Z. A. et al. Optical coherence tomography compared with intravascular ultrasound and with angiography to guide coronary stent implantation (ILUMIEN III: OPTIMIZE PCI): a randomised controlled trial. Lancet http://dx.doi.org/10.1016/S0140-6736(16)31922-5 (2016)
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Ummarino, D. New OCT-based strategy to guide PCI. Nat Rev Cardiol 14, 2 (2017). https://doi.org/10.1038/nrcardio.2016.188
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DOI: https://doi.org/10.1038/nrcardio.2016.188
