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Nature Reviews Cancer 9, 455 (1 July 2009) | doi:10.1038/nrc2688

Signalling: Hedgehog doesn't...

Gemma K. Alderton

The role of hedgehog signalling as a driver of certain solid tumours is well established and receiving considerable translational development. Data also suggest that hedgehog signalling might be important for the development of leukaemia, potentially identifying additional patients that would benefit from anti-hedgehog therapy.