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Research Highlights
Nature Reviews Cancer 9, 458–459 (1 July 2009) | doi:10.1038/nrc2684
Breast cancer: Prioritizing targets
Abstract
A current priority in cancer research is to identify genetic alterations that are directly involved in tumorigenesis and develop therapies to target them. Arul Chinnaiyan and colleagues have used a prioritization strategy to show that angiotensin II receptor type I (AGTR1) is overexpressed in a subset of breast cancers and that these are sensitive to an AGTR antagonist.
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