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Research Highlights
Nature Reviews Cancer 8, 570–571 (1 August 2008) | doi:10.1038/nrc2453
Angiogenesis: Mini mediator of metastasis suppression
Abstract
Molecules that are expressed exclusively on new vessels growing into a developing tumour are potentially important anchors for targeted tumour therapy. David Cheresh and colleagues have found that an integrin-targeted nanoparticle containing a chemotherapeutic drug can suppress the development of tumour metastases by affecting angiogenesis.
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