Access
To read this article in full you may need to log in, make a payment or gain access through a site license (see right).
Research Highlights
Nature Reviews Cancer 8, 484–485 (1 July 2008) | doi:10.1038/nrc2426
Tumorigenesis: Combined effort
Abstract
Probably only a few mutations drive tumour development and progression, but identifying these and defining a therapeutic route through which to exploit them is not easy. Based on their previous findings that cooperating oncogenic mutations lead to synergistic changes in downstream signalling pathways, Hartmut Land and colleagues have shown that a significant number of such synergistic changes are crucial for tumorigenesis.
To read this article in full you may need to log in, make a payment or gain access through a site license (see right).
