Figures and Tables

From the following article:

Adoptive cell transfer: a clinical path to effective cancer immunotherapy

Steven A. Rosenberg, Nicholas P. Restifo, James C. Yang, Richard A. Morgan & Mark E. Dudley

Nature Reviews Cancer 8, 299-308 (April 2008)

doi:10.1038/nrc2355

Figure 1 - Adoptive cell transfer: a clinical path to effective cancer immunotherapy

Figure 1

The generation of anti-tumour T cells used for adoptive cell therapy.

Figure 2 - Adoptive cell transfer: a clinical path to effective cancer immunotherapy

Figure 2

Examples of objective tumour regressions in patients receiving adoptive cell transfer of autologous anti-tumour lymphocytes following a lymphodepleting preparative regimen.

Figure 3 - Adoptive cell transfer: a clinical path to effective cancer immunotherapy

Figure 3

The steps involved in generating anti-tumour T cells by inserting genes encoding T-cell receptors.

Figure 4 - Adoptive cell transfer: a clinical path to effective cancer immunotherapy

Figure 4

Diagram of the retroviral constructs used to insert T-cell receptor (TCR) genes in T cells.

Table 1 - Adoptive cell transfer: a clinical path to effective cancer immunotherapy

Table 1

Adoptive cell therapy in patients with metastatic melanoma79

Table 2 - Adoptive cell transfer: a clinical path to effective cancer immunotherapy

Table 2

Opportunities for improving ACT for the treatment of human cancer