FIGURE 2 | Timeline to complete various steps in each trial.

From the following article:

Lessons from multidisciplinary translational trials on anti-angiogenic therapy of cancer

Rakesh K. Jain

Nature Reviews Cancer 8, 309-316 (April 2008)

doi:10.1038/nrc2346

Lessons from multidisciplinary translational trials on anti-angiogenic therapy of cancer

a | Rectal carcinoma trial. b | Glioblastoma multiforme trial. IRB, institutional review board; NCI, National Cancer Institute; R21; National Institutes of Health Exploratory/Developmental Research Grant.

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