Supplementary information

From the following article:

Hypoxia and metabolism: Hypoxia, DNA repair and genetic instability

Robert G. Bristow & Richard P. Hill

Nature Reviews Cancer 8, 180-192 (March 2008)

doi:10.1038/nrc2344

Supplementary information S1 ((movie)

A normal diploid fibroblast nucleus with pan-53BP1 staining (red) and minimal gammaH2AX foci (green) under non-irradiated normoxic conditions in G1 phase. See also Fig. 2a.

Supplementary information S2 ((movie)

A non-irradiated anoxic fibroblast nucleus arrested in S-phase with global gammaH2AX activation (green) throughout the chromatin. See also Fig. 2b.

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