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From the Editors

Nature Reviews Cancer 8, 157 (1 March 2008) | doi:10.1038/nrc2352

From the editors

Since the isolation of the MYC oncogene in the early 1980s, numerous concepts that try to explain how this transcription factor contributes to tumorigenesis in so many different types of cancer have been postulated. However, new ideas about MYC-dependent responses and how these might be involved in tumorigenesis are still emerging.