Figures and Tables

From the following article:

DNA repair pathways as targets for cancer therapy

Thomas Helleday, Eva Petermann, Cecilia Lundin, Ben Hodgson & Ricky A. Sharma

Nature Reviews Cancer 8, 193-204 (March 2008)

doi:10.1038/nrc2342

Figure 1 - DNA repair pathways as targets for cancer therapy

Figure 1

Overview of DNA repair pathways involved in repairing toxic DNA lesions formed by cancer treatments.

Figure 2 - DNA repair pathways as targets for cancer therapy

Figure 2

Synthetic lethal interactions to identify molecular targets for inhibitors of DNA repair.

Table 1 - DNA repair pathways as targets for cancer therapy

Table 1

Ongoing clinical trials of small-molecule inhibitors of the DNA damage response and related signalling pathways

Table 2 - DNA repair pathways as targets for cancer therapy

Table 2

Synthetic lethal interactions of DNA repair and cell cycle checkpoint genes implicated in cancer by pathway