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Research Highlights

Nature Reviews Cancer 8, 906–907 (1 December 2008) | doi:10.1038/nrc2551

Signalling: Making more of a mark

Meera Swami

Melanomas are resistant to many standard therapies and often metastasize, prompting an intensive search for novel therapeutic targets. A recent study has highlighted a role for Notch signalling in melanoma development under hypoxic conditions.