Figures and Tables
From the following article:
Insights from transgenic mouse models of ERBB2-induced breast cancer
Josie Ursini-Siegel, Babette Schade, Robert D. Cardiff & William J. Muller
Nature Reviews Cancer 7, 389-397 (May 2007)
doi:10.1038/nrc2127
Figure 1
Generation of oncogenic ERBB2 variants by somatic mutation or alternative splicing.
Figure 2
Signalling pathways that regulate ERBB2-mediated transformation.
Figure 3
Comparison of the MMTV–NEU-NDL and the knock-in mouse model.
Figure 4
Similarity between the ERBB2 amplicons in knock-in-derived mammary tumours and primary human breast cancer.
Figure 5
A histological comparison of ERBB2-based mouse models with ERBB2-positive human breast cancer.
