Review
Nature Reviews Cancer 7, 949-960 (December 2007) | doi:10.1038/nrc2288
There is an Erratum (1 January 2008) associated with this article.
Innovations in image-guided radiotherapy
Dirk Verellen1, Mark De Ridder1, Nadine Linthout1, Koen Tournel1, Guy Soete1 & Guy Storme1 About the authors
Abstract
The limited ability to control for the location of a tumour compromises the accuracy with which radiation can be delivered to tumour-bearing tissue. The resultant requirement for larger treatment volumes to accommodate target uncertainty restricts the radiation dose because more surrounding normal tissue is exposed. With image-guided radiotherapy (IGRT) these volumes can be optimized and tumoricidal doses can be delivered, achieving maximal tumour control with minimal complications. Moreover, with the ability of high-precision dose delivery and real-time knowledge of the target volume location, IGRT has initiated the exploration of new indications for radiotherapy, some of which were previously considered infeasible.
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Author affiliations
- UZ Brussel, Oncologisch Centrum, Radiotherapie, Laarbeeklaan 101, B-1090 Brussels, Belgium.
Correspondence to: Dirk Verellen1 Email: dirk.verellen@uzbrussel.be
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