Review
Nature Reviews Cancer 5, 113-125 (February 2005) | doi:10.1038/nrc1546
Nature and nurture – lessons from chemical carcinogenesis
Andreas Luch1 About the author
Abstract
The roles of genetic constitution versus environmental factors in cancer development have been a matter of debate even long before the discovery of 'oncogenes'. Evidence from epidemiological, occupational and migration studies has consistently pointed to environmental factors as the major contributing factors to cancer, so it seems reasonable to discuss the importance of chemical carcinogenesis in the present 'age of cancer genetics'.
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Author affiliations
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Massachusetts Institute of Technology, Center for Cancer Research, 77 Massachusetts Avenue, E17-132, Cambridge, Massachusetts 02319, USA.
Email: luch@mit.edu
Published online 20 January 2005
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