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Review

Nature Reviews Cancer 5, 965–976 (1 December 2005) | doi:10.1038/nrc1750

Recent progress in the battle between oncolytic viruses and tumours

Kelley A. Parato , Donna Senger , Peter A. J. Forsyth & John C. Bell

In the past 5 years, the field of oncolytic virus research has matured significantly and is moving past the stage of being a laboratory novelty into a new era of preclinical and clinical trials. What have recent anticancer trials of oncolytic viruses taught us about this exciting new line of therapeutics?