Figures and Tables
From the following article:
The role of the unfolded protein response in tumour development: friend or foe?
Yanjun Ma & Linda M. Hendershot
Nature Reviews Cancer 4, 966-977 (December 2004)
doi:10.1038/nrc1505
Figure 1
Schematic of endoplasmic reticulum functions under non-stress conditions.
Figure 2
Downstream elements of the unfolded protein response and potential stages of tumour development where it might contribute or interfere.
Figure 3
The pro- and anti-apoptotic roles of the unfolded protein response pathway in normal and malignant cells.
Figure 4
Aspects of the mammalian unfolded protein response that might cause increased resistance to topoisomeras-II-targeting drugs like etoposide (blue and grey) or increased sensitivity to DNA-crosslinking agents like cisplatin (green).
