Perspectives

Nature Reviews Cancer 3, 380-387 (May 2003) | doi:10.1038/nrc1071

TimelinePhotodynamic therapy for cancer

Dennis E.J.G.J. Dolmans1, Dai Fukumura1 & Rakesh K. Jain1  About the authors

Top

The therapeutic properties of light have been known for thousands of years, but it was only in the last century that photodynamic therapy (PDT) was developed. At present, PDT is being tested in the clinic for use in oncology — to treat cancers of the head and neck, brain, lung, pancreas, intraperitoneal cavity, breast, prostate and skin. How does PDT work, and how can it be used to treat cancer and other diseases?

Author affiliations

  1. Edwin L. Steele Laboratory for Tumor Biology, Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA.

Correspondence to: Dai Fukumura1 Email: dai@steele.mgh.harvard.edu

Correspondence to: Rakesh K. Jain1 Email: jain@steele.mgh.harvard.edu

MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated

RESEARCH
Foscan® (mTHPC) photosensitized macrophage activation: enhancement of phagocytosis, nitric oxide release and tumour necrosis factor-alpha-mediated cytolytic activity
British Journal of Cancer Research Article (01 Sep 1999)
Nitric oxide production by tumour tissue: impact on the response to photodynamic therapy
British Journal of Cancer Research Article (01 Jun 2000)
Mechanism of colon cancer cell apoptosis mediated by pyropheophorbide-a methylester photosensitization
Oncogene Original Article (06 Jul 2001)
Role of cytokines in photodynamic therapy-induced local and systemic inflammation
British Journal of Cancer Original Article (02 Jun 2003)
Selective accumulation of ALA-induced PpIX and photodynamic effect in chemically induced hepatocellular carcinoma
British Journal of Cancer Original Article (18 Aug 2003)
See all 28 matches for Research

Extra navigation

Subscribe

Subscribe to Nature Reviews Cancer

Search PubMed for

natureproducts


Advertisement