Perspectives
Nature Reviews Cancer 3, 217-226 (March 2003) | doi:10.1038/nrc1010
Focus on: Early detection
Opinion: Translational approaches to improving cervical screening
Peter Baldwin1, Ronald Laskey1 & Nicholas Coleman1 About the authors
Abstract
Screening programmes for cervical cancer using the current test — the Pap smear — have markedly reduced the incidence of the disease. However, an individual Pap test is of limited sensitivity and is difficult and expensive to perform. Increased understanding of the molecular pathogenesis of cervical cancer indicates that new approaches to screening might offer increased accuracy, affordability and the potential for automation. Such approaches exemplify how improved understanding of the biology of neoplasia might be translated into clinical benefit.
Author affiliations
- Peter Baldwin, Ronald Laskey and Nicholas Coleman are at the MRC Cancer Cell Unit, Hutchison/MRC Research Centre, Hills Road, Cambridge CB2 2XZ, UK.
Correspondence to: Nicholas Coleman1 Email: nc109@cam.ac.uk
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