Figures and Tables

From the following article:

The 14-3-3 cancer connection

Heiko Hermeking

Nature Reviews Cancer 3, 931-943 (December 2003)

doi:10.1038/nrc1230

Figure 1 - The 14-3-3 cancer connection

Figure 1

14-3-3 proteins: 'molecular anvils' that mediate conformational changes or steric hindrance, with functional consequences.

Figure 2 - The 14-3-3 cancer connection

Figure 2

The diverse roles of 14-3-3 proteins in cell-cycle regulation.

Figure 3 - The 14-3-3 cancer connection

Figure 3

DNA damage induces 14-3-3 functions upstream and downstream of p53.

Figure 4 - The 14-3-3 cancer connection

Figure 4

Function of 14-3-3 proteins in the regulation of BAD activity and apoptosis.

Figure 5 - The 14-3-3 cancer connection

Figure 5

14-3-3sigma regulation in normal and cancer cells.

Figure 6 - The 14-3-3 cancer connection

Figure 6

Therapeutic interference with 14-3-3 functions.

Table 1 - The 14-3-3 cancer connection

Table 1

Frequency of CpG methylation of 14-3-3sigma in different types of carcinoma