Figures and Tables
From the following article:
Aromatase inhibitors for breast cancer: lessons from the laboratory
Stephen R.D. Johnston & Mitch Dowsett
Nature Reviews Cancer 3, 821-831 (November 2003)
doi:10.1038/nrc1211
Figure 1
Mechanism of action of aromatase inhibitors and tamoxifen.
Figure 2
Molecular effects of tamoxifen and oestrogen deprivation on oestrogen receptor.
Figure 3
Endocrine treatment of xenografts.
Figure 4
Control of aromatase expression in breast carcinomas.
Figure 5
Molecular structures of aromatase inhibitors in clinical use.
Figure 6
Side effects of anastrozole compared with tamoxifen.
Figure 7
Signalling pathways between cell-surface growth-factor receptors and nuclear oestrogen receptor.
Table 1
Trials of third-generation aromatase inhibitors in advanced breast cancer
