Glossary

ACYCLIC NUCLEOSIDE PHOSPHONATE A drug that blocks the replication of several virus types.

CELLULAR IMMUNE RESPONSE An adaptive immune response, directed against a pathogen, that is mediated by antigen-specific lymphocytes.

DYSPLASIA An early stage in cancer progression, which is characterized by increased cell proliferation and architectural disarray at the tissue level.

EPISOME An independent DNA element, such as a plasmid, that can replicate extrachromosomally or that can be maintained by integration into the genome of the host.

HUMORAL IMMUNE REPONSE A specific immune response, directed against a pathogen, that is mediated by antibodies.

IATROGENIC TRANSMISSION Transmission of infections by a physician.

IMMUNOMODULATORY DRUG A drug that modifies the immune system.

KOILOCYTE A papillomavirus particle-producing cell that acquires an 'owl-eye' shape due to the shrinkage of the nucleus, and a translucent halo that surrounds the nucleus.

LARYNGEAL PAPILLOMA A benign tumour of the larynx.

POLYVALENT VACCINE A vaccine that binds to, or generates an immune response against, more than one thing. In this case, several human papillomavirus types.

SYNCARCINOGENIC EFFECT Synergism between two factors, each of them able to induce cancer.

VIRUS-LIKE PARTICLE (VLP). Empty shell of a virus particle, without genetic material, that is produced by genetic engineering.