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Nature Reviews Cancer 2, 957-964 (December 2002) | doi:10.1038/nrc947

OpinionSV40 and human tumours: myth, association or causality?

Adi F. Gazdar1, Janet S. Butel2 & Michele Carbone3  About the authors

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An increasing number of scientific reports have described evidence for a polyomavirus, simian virus 40, in a highly select group of human tumours. How did a simian virus infect humans and is the virus a passenger in tumours or is it important in their pathogenesis?

Author affiliations

  1. Hamon Center for Therapeutic Oncology Research and Department of Pathology, University of Texas Southwestern Medical Centre, Dallas, Texas 75390, USA.
  2. Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas 77030, USA.
  3. Cardinal Bernardin Cancer Centre and Department of Pathology, Loyola University Chicago, Maywood, Illinois 60153, USA.

Correspondence to: Adi F. Gazdar1 Correspondence to:Email: adi.gazdar@utsouthwestern.edu

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REFERENCE
Polyomaviruses
Nature Encyclopaedia of Life Sciences
Poliovirus
Nature Encyclopaedia of Life Sciences

RESEARCH
Thirty-five year mortality following receipt of SV40- contaminated polio vaccine during the neonatal period
British Journal of Cancer Research Article (01 Nov 2001)
Notch-1 induction, a novel activity of SV40 required for growth of SV40-transformed human mesothelial cells
Oncogene Original Article (09 Jan 2003)
See all 8 matches for Research

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