Figures and Tables
From the following article:
c-MYC: more than just a matter of life and death
Stella Pelengaris, Mike Khan & Gerard Evan
Nature Reviews Cancer 2, 764-776 (October 2002)
doi:10.1038/nrc904
Figure 1
Functional domains of human c-MYC protein.
Figure 2
c-MYC promotes G1?S progression through gene activation and repression.
Figure 3
MYC?MAX and MAD?MAX complexes regulate gene activation through chromatin remodelling.
Figure 4
Pathways involving c-MYC and apoptosis.
Figure 5
Suppression of c-MYC-induced apoptosis exposes several oncogenic properties of c-MYC.
Figure 6
Tumour regression following de-activation of initiating oncogenic lesion.
Table 1
Use of regulatable transgenic mouse models of cancer to test tumour regression
