Figures and Tables

From the following article:

Histone deacetylases and cancer: causes and therapies

Paul A. Marks, Richard A. Rifkind, Victoria M. Richon, Ronald Breslow, Thomas Miller & William K. Kelly

Nature Reviews Cancer 1, 194-202 (December 2001)

doi:10.1038/35106079

Figure 1 - Histone deacetylases and cancer: causes and therapies

Figure 1

Schematic of the structure of histones in nucleosomes.

Figure 2 - Histone deacetylases and cancer: causes and therapies

Figure 2

Proposed mechanism of action of histone deacetylase inhibitors.

Figure 3 - Histone deacetylases and cancer: causes and therapies

Figure 3

Structure of SAHA bound to an HDAC-like protein.

Table 1 - Histone deacetylases and cancer: causes and therapies

Table 1

Characteristics of histone acetyltransferase families

Table 2 - Histone deacetylases and cancer: causes and therapies

Table 2

Characteristics of histone deacetylases

Table 3 - Histone deacetylases and cancer: causes and therapies

Table 3

Histone deacetylase inhibitors