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Figure 2 - Proposed mechanism of 2-hydroxyethidium (2-OH-E+) formation from the reaction between hydroethidine (HE) and O2filled circle-.

From the following article

Detection of 2-hydroxyethidium in cellular systems: a unique marker product of superoxide and hydroethidine

Jacek Zielonka, Jeannette Vasquez-Vivar & Balaraman Kalyanaraman

Nature Protocols 3, 8 - 21 (2008) Published online: 20 December 2007

doi:10.1038/nprot.2007.473

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