ADVANCE ONLINE PUBLICATION
The latest research papers, published online ahead of print. These online versions are definitive and may be cited using the digital object identifier (DOI).
About advance online publication
Reviews
November 25 2009
Probing Compulsive and Impulsive Behaviors, from Animal Models to Endophenotypes: A Narrative Review
Naomi A Fineberg, Marc N Potenza, Samuel R Chamberlain, Heather A Berlin, Lara Menzies, Antoine Bechara, Barbara J Sahakian, Trevor W Robbins, Edward T Bullmore and Eric Hollander
Neuropsychopharmacology advance online publication, November 25, 2009; doi:10.1038/npp.2009.185
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Original Articles
November 25 2009
Molecular Mechanisms of Action and In Vivo Validation of an M4 Muscarinic Acetylcholine Receptor Allosteric Modulator with Potential Antipsychotic Properties
Katie Leach, Richard E Loiacono, Christian C Felder, David L McKinzie, Adrian Mogg, David B Shaw, Patrick M Sexton and Arthur Christopoulos
Neuropsychopharmacology advance online publication, November 25, 2009; doi:10.1038/npp.2009.194
Abstract | Full Text | PDF | Supplementary information
November 18 2009
Opposite Effects of 
-9-Tetrahydrocannabinol and Cannabidiol on Human Brain Function and Psychopathology
Sagnik Bhattacharyya, Paul D Morrison, Paolo Fusar-Poli, Rocio Martin-Santos, Stefan Borgwardt, Toby Winton-Brown, Chiara Nosarti, Colin M O' Carroll, Marc Seal, Paul Allen, Mitul A Mehta, James M Stone, Nigel Tunstall, Vincent Giampietro, Shitij Kapur, Robin M Murray, Antonio W Zuardi, José A Crippa, Zerrin Atakan and Philip K McGuire
Neuropsychopharmacology advance online publication, November 18, 2009; doi:10.1038/npp.2009.184
Antidepressant-Like Effects of 
-Opioid Receptor Antagonists in Wistar Kyoto Rats
Gregory V Carr, Debra A Bangasser, Thelma Bethea, Matthew Young, Rita J Valentino and Irwin Lucki
Neuropsychopharmacology advance online publication, November 18, 2009; doi:10.1038/npp.2009.183
Separable Roles of the Nucleus Accumbens Core and Shell in Context- and Cue-Induced Alcohol-Seeking
Nadia Chaudhri, Lacey L Sahuque, William W Schairer and Patricia H Janak
Neuropsychopharmacology advance online publication, November 18, 2009; doi:10.1038/npp.2009.187
The Role of Glutamate Receptor Redistribution in Locomotor Sensitization to Cocaine
Carrie R Ferrario, Xuan Li, Xiaoting Wang, Jeremy M Reimers, Jamie L Uejima and Marina E Wolf
Neuropsychopharmacology advance online publication, November 18, 2009; doi:10.1038/npp.2009.190
Abstract | Full Text | PDF | Supplementary information
Polymorphisms in GRIK4, HTR2A, and FKBP5 Show Interactive Effects in Predicting Remission to Antidepressant Treatment
Sonja Horstmann, Susanne Lucae, Andreas Menke, Johannes M Hennings, Marcus Ising, Darina Roeske, Bertram Müller-Myhsok, Florian Holsboer and Elisabeth B Binder
Neuropsychopharmacology advance online publication, November 18, 2009; doi:10.1038/npp.2009.180
Valproate and Amitriptyline Exert Common and Divergent Influences on Global and Gene Promoter-Specific Chromatin Modifications in Rat Primary Astrocytes
Tatjana Perisic, Nicole Zimmermann, Thomas Kirmeier, Maria Asmus, Francesca Tuorto, Manfred Uhr, Florian Holsboer, Theo Rein and Jürgen Zschocke
Neuropsychopharmacology advance online publication, November 18, 2009; doi:10.1038/npp.2009.188
Abstract | Full Text | PDF | Supplementary information
November 11 2009
Smoking Reduces Conflict-Related Anterior Cingulate Activity in Abstinent Cigarette Smokers Performing a Stroop Task
Allen Azizian, Liam J Nestor, Doris Payer, John R Monterosso, Arthur L Brody and Edythe D London
Neuropsychopharmacology advance online publication, November 11, 2009; doi:10.1038/npp.2009.186
Neural Substrates of Alcohol-Induced Smoking Urge in Heavy Drinking Nondaily Smokers
Andrea King, Patrick McNamara, Michael Angstadt and K Luan Phan
Neuropsychopharmacology advance online publication, November 11, 2009; doi:10.1038/npp.2009.177
Pimavanserin, a Serotonin2A Receptor Inverse Agonist, for the Treatment of Parkinson's Disease Psychosis
Herbert Y Meltzer, Roger Mills, Stephen Revell, Hilde Williams, Ann Johnson, Daun Bahr and Joseph H Friedman
Neuropsychopharmacology advance online publication, November 11, 2009; doi:10.1038/npp.2009.176
November 4 2009
-Conotoxin MII-Sensitive Nicotinic Acetylcholine Receptors in the Nucleus Accumbens Shell Regulate Progressive Ratio Responding Maintained by Nicotine
Darlene H Brunzell, Karen E Boschen, Elizabeth S Hendrick, Patrick M Beardsley and J Michael McIntosh
Neuropsychopharmacology advance online publication, November 4, 2009; doi:10.1038/npp.2009.171
Abstract | Full Text | PDF | Supplementary information
Stress at Learning Facilitates Memory Formation by Regulating AMPA Receptor Trafficking Through a Glucocorticoid Action
Lisa Conboy and Carmen Sandi
Neuropsychopharmacology advance online publication, November 4, 2009; doi:10.1038/npp.2009.172
Abstract | Full Text | PDF | Supplementary information
More Aroused, Less Fatigued: Fatty Acid Amide Hydrolase Gene Polymorphisms Influence Acute Response to Amphetamine
Andrea M Dlugos, Ajna Hamidovic, Colin A Hodgkinson, David Goldman, Abraham A Palmer and Harriet de Wit
Neuropsychopharmacology advance online publication, November 4, 2009; doi:10.1038/npp.2009.166
Abstract | Full Text | PDF | Supplementary information
Reversible Inhibitors of Monoamine Oxidase-A (RIMAs): Robust, Reversible Inhibition of Human Brain MAO-A by CX157
Joanna S Fowler, Jean Logan, Albert J Azzaro, Robert M Fielding, Wei Zhu, Amy K Poshusta, Daniel Burch, Barry Brand, James Free, Mahnaz Asgharnejad, Gene-Jack Wang, Frank Telang, Barbara Hubbard, Millard Jayne, Payton King, Pauline Carter, Scott Carter, Youwen Xu, Colleen Shea, Lisa Muench, David Alexoff, Elena Shumay, Michael Schueller, Donald Warner and Karen Apelskog-Torres
Neuropsychopharmacology advance online publication, November 4, 2009; doi:10.1038/npp.2009.167
Multicenter Analysis of the SLC6A3/DAT1 VNTR Haplotype in Persistent ADHD Suggests Differential Involvement of the Gene in Childhood and Persistent ADHD
Barbara Franke, Alejandro Arias Vasquez, Stefan Johansson, Martine Hoogman, Jasmin Romanos, Andrea Boreatti-Hümmer, Monika Heine, Christian P Jacob, Klaus-Peter Lesch, Miguel Casas, Marta Ribasés, Rosa Bosch, Cristina Sánchez-Mora, Núria Gómez-Barros, Noèlia Fernàndez-Castillo, Mònica Bayés, Anne Halmøy, Helene Halleland, Elisabeth T Landaas, Ole B Fasmer, Per M Knappskog, Angelien J G A M Heister, Lambertus A Kiemeney, J J Sandra Kooij, A Marije Boonstra, Cees C Kan, Philip Asherson, Stephen V Faraone, Jan K Buitelaar, Jan Haavik, Bru Cormand, Josep Antoni Ramos-Quiroga and Andreas Reif
Neuropsychopharmacology advance online publication, November 4, 2009; doi:10.1038/npp.2009.170
Abstract | Full Text | PDF | Supplementary information
Gamma and Delta Neural Oscillations and Association with Clinical Symptoms under Subanesthetic Ketamine
L Elliot Hong, Ann Summerfelt, Robert W Buchanan, Patricio O'Donnell, Gunvant K Thaker, Martin A Weiler and Adrienne C Lahti
Neuropsychopharmacology advance online publication, November 4, 2009; doi:10.1038/npp.2009.168
Early Response to Antipsychotic Drug Therapy as a Clinical Marker of Subsequent Response in the Treatment of Schizophrenia
Bruce J Kinon, Lei Chen, Haya Ascher-Svanum, Virginia L Stauffer, Sara Kollack-Walker, Wei Zhou, Shitij Kapur and John M Kane
Neuropsychopharmacology advance online publication, November 4, 2009; doi:10.1038/npp.2009.164
FosB Null Mutant Mice Show Enhanced Methamphetamine Neurotoxicity: Potential Involvement of FosB in Intracellular Feedback Signaling and Astroglial Function
Kumi O Kuroda, Veravej G Ornthanalai, Tadafumi Kato and Niall P Murphy
Neuropsychopharmacology advance online publication, November 4, 2009; doi:10.1038/npp.2009.169
Gray Matter Alterations in Obsessive–Compulsive Disorder: An Anatomic Likelihood Estimation Meta-Analysis
Jean-Yves Rotge, Nicolas Langbour, Dominique Guehl, Bernard Bioulac, Nematollah Jaafari, Michele Allard, Bruno Aouizerate and Pierre Burbaud
Neuropsychopharmacology advance online publication, November 4, 2009; doi:10.1038/npp.2009.175
Abstract | Full Text | PDF | Supplementary information
Brain Serotonin Transporter Occupancy by Oral Sibutramine Dosed to Steady State: A PET Study Using 11C-DASB in Healthy Humans
Peter S Talbot, Stefan Bradley, Cyril P Clarke, Kola O Babalola, Andrew W Philipp, Gavin Brown, Adam W McMahon and Julian C Matthews
Neuropsychopharmacology advance online publication, November 4, 2009; doi:10.1038/npp.2009.182
Common and Unique Biological Pathways Associated with Smoking Initiation/Progression, Nicotine Dependence, and Smoking Cessation
Ju Wang and Ming D Li
Neuropsychopharmacology advance online publication, November 4, 2009; doi:10.1038/npp.2009.178
Stress Enhances Retrieval of Drug-Related Memories in Abstinent Heroin Addicts
Li-Yan Zhao, Jie Shi, Xiao-Li Zhang, David H Epstein, Xiang-Yang Zhang, Yu Liu, Thomas R Kosten and Lin Lu
Neuropsychopharmacology advance online publication, November 4, 2009; doi:10.1038/npp.2009.179
October 28 2009
Effects of Treatment for Tobacco Dependence on Resting Cerebral Glucose Metabolism
Matthew R Costello, Mark A Mandelkern, Stephen Shoptaw, Stephanie Shulenberger, Stephanie K Baker, Anna L Abrams, Catherine Xia, Edythe D London and Arthur L Brody
Neuropsychopharmacology advance online publication, October 28, 2009; doi:10.1038/npp.2009.165
October 21 2009
Low Doses of 17-Estradiol and 17
-Estradiol Facilitate, Whereas Higher Doses of Estrone and 17- and 17-Estradiol Impair, Contextual Fear Conditioning in Adult Female Rats
Cindy K Barha, Gemma L Dalton and Liisa AM Galea
Neuropsychopharmacology advance online publication, October 21, 2009; doi:10.1038/npp.2009.161
Dissociable Control of Impulsivity in Rats by Dopamine D2/3 Receptors in the Core and Shell Subregions of the Nucleus Accumbens
Morgane Besson, David Belin, Ruth McNamara, David EH Theobald, Aude Castel, Victoria L Beckett, Ben M Crittenden, Amy H Newman, Barry J Everitt, Trevor W Robbins and Jeffrey W Dalley
Neuropsychopharmacology advance online publication, October 21, 2009; doi:10.1038/npp.2009.162
Abstract | Full Text | PDF | Supplementary information
Serotonergic and Noradrenergic Modulation of Emotion Processing by Single Dose Antidepressants
Annette Beatrix Brühl, Tina Kaffenberger and Uwe Herwig
Neuropsychopharmacology advance online publication, October 21, 2009; doi:10.1038/npp.2009.159
Abstract | Full Text | PDF | Supplementary information
Sex Differences in Social Interaction in Rats: Role of the Immediate-Early Gene zif268
Ashley Stack, Nicole Carrier, David Dietz, Fiona Hollis, Jamie Sorenson and Mohamed Kabbaj
Neuropsychopharmacology advance online publication, October 21, 2009; doi:10.1038/npp.2009.163
October 14 2009
Chronic Creatine Supplementation Alters Depression-like Behavior in Rodents in a Sex-Dependent Manner
Patricia J Allen, Kristen E D'Anci, Robin B Kanarek and Perry F Renshaw
Neuropsychopharmacology advance online publication, October 14, 2009; doi:10.1038/npp.2009.160
The Stanley Neuropathology Consortium Integrative Database: a Novel, Web-Based Tool for Exploring Neuropathological Markers in Psychiatric Disorders and the Biological Processes Associated with Abnormalities of Those Markers
Sanghyeon Kim and Maree J Webster
Neuropsychopharmacology advance online publication, October 14, 2009; doi:10.1038/npp.2009.151
Abstract | Full Text | PDF | Supplementary information
A Cannabinoid CB1 Receptor Antagonist Ameliorates Impairment of Recognition Memory on Withdrawal from MDMA (Ecstasy)
Yoko Nawata, Takato Hiranita and Tsuneyuki Yamamoto
Neuropsychopharmacology advance online publication, October 14, 2009; doi:10.1038/npp.2009.158
September 30 2009
Reduced Occipital and Prefrontal Brain Volumes in Dysbindin-Associated Schizophrenia
Gary Donohoe, Thomas Frodl, Derek Morris, Ilaria Spoletini, Dara M Cannon, Andrea Cherubini, Carlo Caltagirone, Paola Bossù, Colm McDonald, Michael Gill, Aiden P Corvin and Gianfranco Spalletta
Neuropsychopharmacology advance online publication, September 30, 2009; doi:10.1038/npp.2009.140
An Animal Model of Genetic Vulnerability to Behavioral Disinhibition and Responsiveness to Reward-Related Cues: Implications for Addiction
Shelly B Flagel, Terry E Robinson, Jeremy J Clark, Sarah M Clinton, Stanley J Watson, Phillip Seeman, Paul E M Phillips and Huda Akil
Neuropsychopharmacology advance online publication, September 30, 2009; doi:10.1038/npp.2009.142
Abstract | Full Text | PDF | Supplementary information
Reversal-Specific Learning Impairments After a Binge Regimen of Methamphetamine in Rats: Possible Involvement of Striatal Dopamine
Alicia Izquierdo, Annabelle M Belcher, Lori Scott, Victor A Cazares, Jack Chen, Steven J O'Dell, Melissa Malvaez, Tiffany Wu and John F Marshall
Neuropsychopharmacology advance online publication, September 30, 2009; doi:10.1038/npp.2009.155
Fos After Single and Repeated Self-Administration of Cocaine and Saline in the Rat: Emphasis on the Basal Forebrain and Recalibration of Expression
Daniel S Zahm, Mary L Becker, Alexander J Freiman, Sara Strauch, Beth DeGarmo, Stefanie Geisler, Gloria E Meredith and Michela Marinelli
Neuropsychopharmacology advance online publication, September 30, 2009; doi:10.1038/npp.2009.149
September 23 2009
Effects of Extended Cocaine Access and Cocaine Withdrawal on Choice Between Cocaine and Food in Rhesus Monkeys
Matthew L Banks and S Stevens Negus
Neuropsychopharmacology advance online publication, September 23, 2009; doi:10.1038/npp.2009.154
Aggression, Suicidality, and Intermittent Explosive Disorder: Serotonergic Correlates in Personality Disorder and Healthy Control Subjects
Emil F Coccaro, Royce Lee and Richard J Kavoussi
Neuropsychopharmacology advance online publication, September 23, 2009; doi:10.1038/npp.2009.148
Voluntary Exercise and Sucrose Consumption Enhance Cannabinoid CB1 Receptor Sensitivity in the Striatum
Valentina De Chiara, Francesco Errico, Alessandra Musella, Silvia Rossi, Giorgia Mataluni, Lucia Sacchetti, Alberto Siracusano, Maura Castelli, Francesca Cavasinni, Giorgio Bernardi, Alessandro Usiello and Diego Centonze
Neuropsychopharmacology advance online publication, September 23, 2009; doi:10.1038/npp.2009.141
Involvement of Hippocampal Jun-N Terminal Kinase Pathway in the Enhancement of Learning and Memory by Nicotine
Justin W Kenney, Cédrick Florian, George S Portugal, Ted Abel and Thomas J Gould
Neuropsychopharmacology advance online publication, September 23, 2009; doi:10.1038/npp.2009.153
Abstract | Full Text | PDF | Supplementary information
Increased Basal Synaptic Inhibition of Hippocampal Area CA1 Pyramidal Neurons by an Antiepileptic Drug that Enhances I H
Bi-Wen Peng, Jason A Justice, Kun Zhang, Xiao-hua He and Russell M Sanchez
Neuropsychopharmacology advance online publication, September 23, 2009; doi:10.1038/npp.2009.150
September 16 2009
The Glycine Transporter-1 Inhibitor SSR103800 Displays a Selective and Specific Antipsychotic-like Profile in Normal and Transgenic Mice
Denis Boulay, Olivier Bergis, Patrick Avenet and Guy Griebel
Neuropsychopharmacology advance online publication, September 16, 2009; doi:10.1038/npp.2009.144
Serial Mitogen-Stimulated Cytokine Production from Continuously Ill Patients with Schizophrenia
Mark H Rapaport and Catherine Bresee
Neuropsychopharmacology advance online publication, September 16, 2009; doi:10.1038/npp.2009.145
Mechanisms of Locomotor Sensitization to Drugs of Abuse in a Two-Injection Protocol
Emmanuel Valjent, Jesus Bertran-Gonzalez, Benjamin Aubier, Paul Greengard, Denis Hervé and Jean-Antoine Girault
Neuropsychopharmacology advance online publication, September 16, 2009; doi:10.1038/npp.2009.143
Abstract | Full Text | PDF | Supplementary information
September 9 2009
D-cycloserine Deters Reacquisition of Cocaine Self-Administration by Augmenting Extinction Learning
Bríd Á Nic Dhonnchadha, Jonathan J Szalay, Cindy Achat-Mendes, Donna M Platt, Michael W Otto, Roger D Spealman and Kathleen M Kantak
Neuropsychopharmacology advance online publication, September 9, 2009; doi:10.1038/npp.2009.139
Abstract | Full Text | PDF | Supplementary information
March 19 2008
Future Suicide Attempt and Responses to Serotonergic Challenge FREE
John G Keilp, Maria A Oquendo, Barbara H Stanley, Ainsley K Burke, Thomas B Cooper, Kevin M Malone and J John Mann
Neuropsychopharmacology advance online publication, March 19, 2008; doi:10.1038/npp.2008.28
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Neuropsychopharmacology Reviews
October 7 2009
The Reward Circuit: Linking Primate Anatomy and Human Imaging
Suzanne N Haber and Brian Knutson
Neuropsychopharmacology advance online publication, October 7, 2009; doi:10.1038/npp.2009.129
September 30 2009
Normal Development of Brain Circuits
Gregory Z Tau and Bradley S Peterson
Neuropsychopharmacology advance online publication, September 30, 2009; doi:10.1038/npp.2009.115
September 23 2009
Human and Rodent Homologies in Action Control: Corticostriatal Determinants of Goal-Directed and Habitual Action
Bernard W Balleine and John P O'Doherty
Neuropsychopharmacology advance online publication, September 23, 2009; doi:10.1038/npp.2009.131
The Episodic Memory System: Neurocircuitry and Disorders
Bradford C Dickerson and Howard Eichenbaum
Neuropsychopharmacology advance online publication, September 23, 2009; doi:10.1038/npp.2009.126
September 16 2009
Attention-Deficit/Hyperactivity Disorder and Attention Networks
George Bush
Neuropsychopharmacology advance online publication, September 16, 2009; doi:10.1038/npp.2009.120
Invasive Circuitry-Based Neurotherapeutics: Stereotactic Ablation and Deep Brain Stimulation for OCD
Benjamin D Greenberg, Scott L Rauch and Suzanne N Haber
Neuropsychopharmacology advance online publication, September 16, 2009; doi:10.1038/npp.2009.128
Abstract | Full Text | PDF | Supplementary information
September 2 2009
Amygdalocortical Circuitry in Schizophrenia: From Circuits to Molecules
Francine M Benes
Neuropsychopharmacology advance online publication, September 2, 2009; doi:10.1038/npp.2009.116
August 26 2009
Changing Fear: The Neurocircuitry of Emotion Regulation
Catherine A Hartley and Elizabeth A Phelps
Neuropsychopharmacology advance online publication, August 26, 2009; doi:10.1038/npp.2009.121
Neurocircuitry of Addiction
George F Koob and Nora D Volkow
Neuropsychopharmacology advance online publication, August 26, 2009; doi:10.1038/npp.2009.110
August 19 2009
Phasic vs Sustained Fear in Rats and Humans: Role of the Extended Amygdala in Fear vs Anxiety
Michael Davis, David L Walker, Leigh Miles and Christian Grillon
Neuropsychopharmacology advance online publication, August 19, 2009; doi:10.1038/npp.2009.109
Executive Function, Neural Circuitry, and Genetic Mechanisms in Schizophrenia
Daniel Paul Eisenberg and Karen Faith Berman
Neuropsychopharmacology advance online publication, August 19, 2009; doi:10.1038/npp.2009.111
Noninvasive techniques for probing neurocircuitry and treating illness: vagus nerve stimulation (VNS), transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS)
Mark S George and Gary Aston-Jones
Neuropsychopharmacology advance online publication, August 19, 2009; doi:10.1038/npp.2009.87
Neurocircuitry of Mood Disorders
Joseph L Price and Wayne C Drevets
Neuropsychopharmacology advance online publication, August 19, 2009; doi:10.1038/npp.2009.104
August 12 2009
Cortico-Basal Ganglia Reward Network: Microcircuitry
Susan R Sesack and Anthony A Grace
Neuropsychopharmacology advance online publication, August 12, 2009; doi:10.1038/npp.2009.93
August 5 2009
The Neural Circuitry of Executive Functions in Healthy Subjects and Parkinson's Disease
Sandra E Leh, Michael Petrides and Antonio P Strafella
Neuropsychopharmacology advance online publication, August 5, 2009; doi:10.1038/npp.2009.88
July 22 2009
The Neurocircuitry of Fear, Stress, and Anxiety Disorders
Lisa M Shin and Israel Liberzon
Neuropsychopharmacology advance online publication, July 22, 2009; doi:10.1038/npp.2009.83
