February 2017 - Volume 42, Issue 3

Immunocytochemistry of an in vitro 3D neocortical organoid model derived from human pluripotent stem cells, which can produce single ventricle-like cavities. This method provides a platform for identifying adverse effects of psychostimulants and pharmaceutical agents, and can be adapted for use in neurodevelopmental disorders. Image courtesy of Jia Chen and Chun-Ting Lee, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, Maryland, USA. For more information, see the paper by Lee et al, npp.2016.156, on page 774.

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