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Differences between chronic marijuana users and controls subjects in brain activation measured using [15O]water PET during a monetary decision-making task. Chronic marijuana users demonstrated greater activity in the cerebellum, among other brain regions, during the decision-making task. Activation is shown overlaid on an average template brain. Cover image courtesy of Dr Jatin G Vaidya, Department of Psychiatry, Carver College of Medicine, University of Iowa, Iowa City, IA, USA.