FIGURE 1
FROM:
Perspective: Translational Studies on Glutamate and Dopamine Neurocircuitry in Addictions: Implications for Addiction Treatment
Evelyn K Lambe and Tony P George
BACK TO ARTICLEFigure 1.

Schematics of human and rodent brains depict how the dopamine projections of the ventral tegmental area (VTA) innervate the nucleus accumbens (N. acc.) and the prefrontal cortex. These dopamine projections have been shown to be important for the modulation of mood, reward, and attention. The series of articles in this issue of the journal highlight the importance of the glutamatergic modulation of dopamine neurons in the VTA in understanding nicotine and other drug addictions. (Adapted from Schultz, 1999; Bailey, 2005.)
