Volume 34 Issue 1, January 2009

Neuropsychopharmacology Reviews: The Next Generation of Progress

The distinct regional localization of peptide and non-peptide binding determinants for the Class-B CRF₁ G-protein coupled receptor.

Commentary

Commentary: Physician–Scientist's Frustrations Fester

Floyd E Bloom

Series:

2009 Neuropsychopharmacology Reviews: CNS Drug Discovery & Development: Challenges and Opportunities
Commentary 12 Dec 2008
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Top of page ⤴

Volume 34 Issue 1, January 2009

Neuropsychopharmacology Reviews: The Next Generation of Progress

Commentary

Commentary: Physician–Scientist's Frustrations Fester

Neuropsychopharmacology Reviews

The Medical and Economic Roles of Pipeline Pharmacogenetics: Alzheimer's Disease as a Model of Efficacy and HLA-B^*5701 as a Model of Safety

Target Identification for CNS Diseases by Transcriptional Profiling

In Vitro and In Vivo Pharmacological Models to Assess Demyelination and Remyelination

Removing Obstacles in Neuroscience Drug Discovery: The Future Path for Animal Models

Non-Human Primates: Model Animals for Developmental Psychopathology

Drugability of Extracellular Targets: Discovery of Small Molecule Drugs Targeting Allosteric, Functional, and Subunit-Selective Sites on GPCRs and Ion Channels

Small Molecule Protein–Protein Interaction Inhibitors as CNS Therapeutic Agents: Current Progress and Future Hurdles

Novel Therapeutic Modalities to Address Nondrugable Protein Interaction Targets

Pharmacogenomics: The Promise of Personalized Medicine for CNS Disorders

Metabolomics: A Global Biochemical Approach to the Study of Central Nervous System Diseases

The Role of Imaging in Proof of Concept for CNS Drug Discovery and Development

Bridging Bench and Practice: Translational Research for Schizophrenia and Other Psychotic Disorders

Challenges in Developing Novel Treatments for Childhood Disorders: Lessons from Research on Anxiety

NIMH Initiatives to Facilitate Collaborations Among Industry, Academia, and Government for the Discovery and Clinical Testing of Novel Models and Drugs for Psychiatric Disorders

Hot Topics

Adult neurogenesis, cell cycle and drug discovery in psychiatry

Targeting nicotinic receptor antagonists as novel pharmacotherapies for tobacco dependence and relapse

RNA editing as a therapeutic target for CNS disorders

The dynorphin/kappa opioid receptor system: a new target for the treatment of addiction and affective disorders?

Protein–protein interactions as therapeutic targets in neuropsychopharmacology

Promise of mGluR2/3 activators in psychiatry

Targeting AMPA and kainate receptors in neurological disease: therapies on the horizon?

Gene expression profiling in blood: new diagnostics in alcoholism and addiction?

From rapid In Vitro screening to rapid In Vivo screening in the drug discovery process

Targeting the serotonin 2C receptor for the treatment of obesity and type 2 diabetes

Turning up the pace of ion channel screening in drug discovery

Lewy body pathology in long-term fetal nigral transplants: is parkinson's disease transmitted from one neural system to another?

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