Neuropsychopharmacology

FIGURE 2

FROM:

MDMA Induces EPSP–Spike Potentiation in Rat Ventral Hippocampus In Vitro Via Serotonin and Noradrenaline Release and Coactivation of 5-HT4 and bold italic beta 1 Receptors

Boris Mlinar, Simona Mascalchi, Raffaella Morini, Filippo Giachi and Renato Corradetti

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Figure 2.

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Concentration-dependence of the increase in population spike amplitude (PSA) induced by N-methyl-3,4-methylenedioxyamphetamine (MDMA). (a) Summary time–courses of effects of indicated MDMA concentrations on PSA (meanplusminusSD; n=8, 13, 86, and 11, slices obtained from 6, 7, 47, and 7 animals, respectively). (b) Superimposed mean time–course of the indicated concentrations of MDMA showing faster PSA increase in response to the application of higher MDMA concentrations.

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